The Genetic Architecture of Behavioral Disorders

Exploring the Role of Epigenetics in Psychiatry

Authors

DOI:

https://doi.org/10.30820/1664-9583-2025-1-57

Keywords:

behavioral disorders, epigenetics, genetic architecture, psychiatry, personalized medicine

Abstract

Behavioral disorders such as depression, schizophrenia, ADHD, and autism spectrum disorders represent a significant challenge in psychiatry due to their complex and multifactorial nature. While traditional models have focused on genetic predispositions, emerging research highlights the critical role of epigenetics in modulating gene expression in response to environmental factors. This literature review explores the genetic architecture of behavioral disorders, emphasizing the influence of epigenetic mechanisms such as DNA methylation, histone modification, and non-coding RNAs. We delve into how these processes contribute to the onset, progression, and transgenerational transmission of psychiatric conditions. Furthermore, we discuss the implications of these findings for personalized treatment strategies and future research directions, underscoring the potential for epigenetic therapies in reshaping psychiatric practice. This review aims to bridge the gap between genetics and environment, offering a comprehensive understanding of how epigenetics can inform the future of psychiatric care.

Author Biography

Kirolos Eskandar

Kirolos Eskandar, Physician, is affiliated with the Diakonie Klinik Mosbach, Germany. He is an independent researcher with a strong academic foundation, holding a Bachelor of Science, a Master of Arts, and a Bachelor of Medicine and Surgery. His clinical experience spans various specialties, including neuropsychiatry and internal medicine, with a focus on diagnosing and treating mental health conditions. He is an author of many articles in the areas such as Medical advancements, Oncology, Psychiatry and serves on the editorial board of the World Journal of Health and Medicine. ORCID ID: 0000-0003-0085-3284

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Published

2025-04-03

How to Cite

Eskandar, K. (2025). The Genetic Architecture of Behavioral Disorders: Exploring the Role of Epigenetics in Psychiatry. Psychotherapie-Wissenschaft, 15(1), 57–63. https://doi.org/10.30820/1664-9583-2025-1-57

Issue

Vol. 15 No. 1 (2025): Intersubjektives Erleben in der Psychotherapie

Section

Original Work

License

Copyright (c) 2025 Kirolos Eskandar

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